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Cheesy Mexican Beef & Penne Bake

Updated on 3 min read

Quick Description

This Cheesy Mexican Beef & Penne Bake is a bold, creamy, and satisfying casserole loaded with seasoned ground beef, tender penne pasta, tomatoes with green chilies, and plenty of melty Mexican cheese. It’s the perfect fusion of taco flavors and baked pasta comfort.

Servings & Timing

  • Serves: 8–10
  • Prep Time: 20 minutes
  • Bake Time: 25–30 minutes
  • Total Time: ~50 minutes

Ingredients List

  • 2 lbs ground beef
  • 1 lb (16 oz) penne pasta
  • 2½ cups Mexican cheese blend, grated (divided)
  • 2 cups (16 oz) sour cream
  • 1 can (10 oz) diced tomatoes with green chilies
  • 1 can (14 oz) crushed tomatoes, undrained
  • 1 small onion, chopped
  • 1–2 cloves garlic, minced
  • 2 tablespoons chili powder
  • ½ teaspoon ground cumin

Instructions

1. Preheat Oven
Preheat oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish.

2. Cook the Pasta
Bring a large pot of salted water to a boil.
Cook penne pasta until al dente according to package directions.
Drain and set aside.

3. Brown the Beef
In a large skillet over medium heat, cook ground beef until browned.
Drain excess grease.

4. Add Flavor
Add chopped onion and cook for 3–4 minutes until softened.
Stir in garlic and cook for 30 seconds.
Add chili powder and cumin, stirring to coat the meat evenly.

5. Add Tomatoes
Stir in diced tomatoes with green chilies and crushed tomatoes.
Simmer for 5–7 minutes.

6. Combine
Reduce heat and stir in sour cream and 1½ cups of cheese until melted and creamy.
Fold in cooked pasta until evenly coated.

7. Assemble & Bake
Pour mixture into prepared baking dish.
Top with remaining 1 cup cheese.
Bake for 25–30 minutes, until bubbly and golden.

8. Rest & Serve
Let rest for 5 minutes before serving.

Nutrition (Per Serving – Approximate)

  • Calories: 520
  • Protein: 34g
  • Carbohydrates: 42g
  • Fat: 26g
  • Fiber: 4g

Benefits

  • High-Protein Meal: Hearty and filling
  • Family-Friendly: Bold but balanced flavors
  • Great for Meal Prep: Reheats well
  • Comfort Food Twist: Taco flavors in pasta form

Additional Notes

  • Adjust chili powder for spice level
  • Use lean ground beef for less grease
  • Add a splash of broth if mixture seems too thick

Dietary Info

  • High-Protein ✔
  • Gluten-Free Option ✖ (use GF pasta)
  • Vegetarian ✖

Brief Introduction

This dish combines everything you love about tacos and baked pasta into one cheesy, comforting casserole. It’s bold, creamy, and perfect for busy weeknights or feeding a crowd.

Step-by-Step Cooking Guide

  1. Boil pasta
  2. Brown beef with onion and garlic
  3. Add spices and tomatoes
  4. Stir in sour cream and cheese
  5. Mix with pasta
  6. Bake until golden

Ingredient Details & Substitutions

  • Ground Beef: Substitute ground turkey or chicken
  • Mexican Cheese Blend: Cheddar and Monterey Jack work well
  • Sour Cream: Greek yogurt can be used for lighter option

Recipe Variations & Serving Suggestions

  • Add black beans for extra texture
  • Top with sliced jalapeños
  • Garnish with fresh cilantro

Storage & Make-Ahead

  • Refrigerator: Store up to 4 days
  • Freezer: Freeze assembled (before baking) up to 2 months
  • Reheat: Oven or microwave

FAQs

Can I make this ahead?
Yes, assemble and refrigerate up to 24 hours before baking.

Can I make it spicier?
Add extra chili powder or diced jalapeños.

Does it freeze well?
Yes, especially before baking.

Optional Personal Story

This recipe became a regular in our dinner rotation because it’s comforting, filling, and always gets clean plates. It’s like taco night—but even easier.

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